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Tirzepatide causes thyroid C-cell tumors in rats, and although its unknown whether tirzepatide causes thyroid C-cell tumors in humans, it is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

The protocol was registered in PROSPERO (ID: CRD420251151333)

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Catabolismo simplemente significa la descomposicin de molculas complejas en molculas ms pequeas

Compound Profile Scientific & Efficacy Data C 35 H 48 N 10 O 15 Molecular Formula 848.81 g/mol Molecular Weight 7-8 minutes (but effects last many hours due to downstream signaling) Half-Life Variable