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We already have that to some extent with neurostimulation and with glutamate like ketamine and esketamine
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This is not a reason to start metformin on its own, but it is a relevant consideration if metformin is already part of the clinical conversation
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Genetic data supports an informed decision but does not guarantee outcome
While this may work short term, it frequently fails over time due to biological resistance mechanisms
Therefore, further research is needed to draw conslusive evidence
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