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There is no clear sign that Wegovy tablets cause any new long-term side effects that are different from semaglutide injections
or (ii) RCTs comparing different AOMs with active drug control
Clinical data from the STEP 1 extension study show that most patients experience weight regain after discontinuation, with research indicating that on average, approximately two-thirds of lost weight returns within one year of stopping treatment
In December 2025, Lilly reported Phase 3 trial results showing participants lost an average of 28.7% of their body weight (~71 lbs) over 68 weeks among the largest average weight-loss results ever reported in a Phase 3 obesity drug trial
Ask whether you qualify for the Medicare GLP-1 Bridge for weight management
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