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It is possible that this relatively selective colonic mucosal involvement may reflect the qualitative or quantitative differences in colonic microbial flora (as opposed to the small intestine)

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Nutrients that Stimulate GLP-1 Secretion (also known as secretagogues) GLP-1 is produced in L cells which are abundant in the lining of the large intestine (Figure 3)

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Jones LL, McDonald DA, Borum PR (2010) Acylcarnitines: role in brain

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