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It's essential not to exceed the prescribed dosage without consulting your doctor

NAD+ levels decline by 40-60% with ageglutathione protects respiratory chain complexes from ROS

For repletion of a confirmed deficiency, I use higher doses, typically 1000 to 2000 mcg per day

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For example, in a new study, patients who first used a daily topical treatment gel containing 0.1% adapalene and 2.5% benzoyl peroxide for 2-4 weeks before undergoing 3 treatments with Sebacia, spaced 1-2 weeks apart, saw an improvement of 66% at 3 months, as compared to those who had Sebacia alone (in the clinical trials), and showed 49% improvement at 3 months