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Proliferation (log 2 doublings, 5 days) of indicated UGDH-deficient cell lines expressing a sgRNA resistant UGDH cDNA or an empty vector under the indicated concentrations of erastin
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Degraded in GI tract Hepatic first-pass processing Absorption varies by formulation Glutathione Injection Bypasses gastrointestinal processing entirely
In fact, the presence of six functional groups in NA allows its octahedral coordination and an optimal structure ideal for chelation of metal ions (Relln-lvarez et al., 2008)
Mechanism of Action The mechanism of action of GHK-Cu relies on its ability to extensively modulate gene expression
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