Semaglutide usually expires within two years from the date of manufacture when stored properly in the refrigerator
Image z-stacks were collected with a step-size of 1 m and rendered as three-dimensional rotational animations using Imaris 8.1.2 software (Supplementary videos 1 and 2)
What we call CNS fatigue really is a problem with one of the main excitatory neurotransmitters (dopamine, adrenaline, glutamate), preventing them to do their job (activating your CNS)
They can assess whether the symptoms might be related to the medication, explore other contributing factors, and determine the most appropriate course of action
In a meta-analysis in T2DM patients, pooled effects analysis demonstrated that GLP-1RAs were associated with a significant improvement in 6-min walk test results (mean difference = 22.3 m, 95% CI:1.64, 42.99) [78]
The 1 mg starting dose looks similar to Mounjaro at 2.5 mg, mild and mostly tolerable