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X-linked recessive: 5 defects which are X-linked- CHO (G6PD deficiency) Lipid metabolism (Fabry's disease, caused by Alpha Galactosidase, which is X-linked recessively inherited) Amino acid metabolism (Type 2 Hyperammonemia) Puri Salvage metabolism- GPRTase defect, which is an enzyme of the Purine Salvage pathway, and the Defect of this enzyme causes Lesch Nyhan Syndrome

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Fasting triggers a cascade of metabolic benefits, including: Increased insulin sensitivity Enhanced GLP-1 secretion Reduced appetite and cravings Improved fat burning Studies show that even short fastslike a 12- to 16-hour fasting windowcan elevate GLP-1 and improve metabolic flexibility

Therefore, the relative increase in Bacteroidetes abundance after Rhein intervention may imply increase SCFA production, which is crucial for alleviating systemic low-grade inflammation and renal injury in ORG