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Xia W et al

Injecting as close as anatomically safe to the target tissue maximises local tissue concentration

This multi-receptor activation enables: GLP-1R activation enhances glucose-dependent insulin secretion and reduces appetite through hypothalamic signaling GIPR activation (highest potency: EC50 0.0643 nM) promotes insulin secretion and modulates lipid metabolism GCGR activation (EC50 5.79 nM) increases energy expenditure and promotes hepatic fat oxidation Combined receptor engagement produces dose-dependent reductions in body weight and improvements in glycemic control Research demonstrates that GLP3s balanced activation across three receptors produces superior metabolic effects compared to single or dual agonists, with phase 2 trials showing up to 24.2% weight reduction in 48 weeks[2]

It does not affect the regulatory position in the United Kingdom, the European Union or anywhere else

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Increases Energy Levels B12 converts the food you consume into usable energy by converting the glucose from carbohydrates and lipids from fat into ATP, a chemical that provides energy to our cells