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Similarly, as a result of the positive findings from the recent DAPA-CKD trial [90], dapagliflozin is now indicated for the treatment of CKD, and can be initiated if eGFR 25 ml/min/1.73 m 2
Recognizing these patterns early can help you build a routine that feels more sustainable and easier to follow long-term
It is plausible that the two siblings may carry different GLP1R genotypes: the sister might harbor the rs6923761 AA variant, which is associated with a higher weight loss rate, while the brother may carry the GG or GA variant that weakens semaglutide efficacy
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