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5-HTT / rats (Slc6a41Hubr) were generated on a Wistar background by N -ethyl- N -nitrosurea (ENU)-induced mutagenesis ( +/ rats that were outcrossed for at least 12 generations with wild-type Wistar rats obtained from Harlan Laboratories (Horst, The Netherlands)
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It shares 94% structural homology with native human GLP-1, the incretin hormone your body produces after eating
( E ) The nuclear localization of mGreenLantern (mGL)-tagged HMP-2 (arrows) is increased in the DTC of glp-1 mutants
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