Label every vial immediately with date, concentration, and expiry
Hormonal interactions are not a documented concern at research doses
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Folate supplementation without adequate B12 can also partially mask B12-related anaemia in routine blood tests, making deficiency harder to detect through a standard CBC alone (Cikot et al., 2001, British Journal of Nutrition)
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The same is true of B vitamin complex supplements, which deliver 50 to 500 micrograms (i.e., 20 to 200% of the RDA), as well as for most supplements containing only vitamin B12, which deliver up to 1,000 micrograms (about 400% of the RDA)