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Taken together, we have highlighted GLP-1 as a novel therapeutic marker for identifying and treating the neuropathology of depression

In contrast, exendin-4 decreased S6K activity in the VMH of lean rats re-fed for four hours [83] (Figure 5)

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PMID 4896351

Key takeaways GLP-1 agonists are a class of drugs that were originally designed to treat type 2 diabetes, but their use has expanded to include weight loss, heart and kidney disease risk reduction, and management of obstructive sleep apnea