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Sakurauchi, Y., Matsumoto, Y., Shinzato, T., Takai, I., Nakamura, Y., Sato, M., Nakai, S., Miwa, M., Morita, H., Miwa, T

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However, before the onset of clinically diagnosable motor symptoms, most patients experience several non-motor symptoms, including depression, apathy, dementia, rapid eye movement (REM), sleep behavior disorder (RBD), and GI-associated disorders, including reduced gastric emptying and constipation (Chaudhuri et al., 2006

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