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Hence NAC works as a glutathione donor preventing NAPQI accumulation Paracetamol metabolism diagram Toxicokinetics: Well absorbed from the small intestine Peak concentration 1-2 hours post ingestion (30 mins for liquid) Small volume of distribution 0.9 L/kg Hepatic metabolism and renal excretion as shown above
therefore, they may attack RBCs, inducing membrane structure changes (erythrocyte shrinkage, membrane blebbing, and PS exposure) and, finally, eryptosis
Oncol Res
Intake-related elevation as the most common explanation Most of the time, a high B12 traces back to something the patient took or was given
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