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15 Further TRIUMPH trials in people with type 2 diabetes and cardiovascular disease are due to be released later in 2026

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All these rats were sacrificed 28 days after injection of monoiodoacetate under anesthesia using 50 mg/kg sodium pentobarbital by intraperitoneal injection

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Beyond serving as energetic substrates, SCFAs exert important endocrine functions by binding to G-proteincoupled receptors, namely FFAR2 (GPR43) and FFAR3 (GPR41), expressed on enteroendocrine L cells and other cell types across rodents and humans (59, 60)

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