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DPP-IV cleaves GLP-1 at the peptide bond between Ala8-Glu9 (Fig
Relationship between intervertebral disc and facet joint degeneration: a probabilistic finite element model study
11 (4), e1004180
Other common side effects associated with GLP-1s include constipation, loss of muscle mass or bone density, and, less commonly, abdominal pain, according to the Obesity Action Coalition
For patients with cardiovascular or kidney disease, SGLT2 inhibitors or GLP-1 receptor agonists (oral or injectable) may be considered as part of first-line therapy for their cardiorenal benefits
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