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At worst, excessive topical use causes local irritation, which resolves when you reduce application

Other Side Effects: Some less common effects (around 2-5%) include dizziness, fatigue, mild nasal congestion or cough, and injection site itching

6 Several of these drugs, such as Wegovy and Zepbound, were approved for use as a treatment for obesity, obstructive sleep apnea, heart attack or stroke prevention in those who have already experienced a cardiovascular event

Topical cosmetic use appears to be well tolerated for most individuals, though long-term systemic applications have not been fully studied

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Experimental studies reported that procedures like choline-induced fecal transplantation from one person to another can also transfer the risk of developing atherosclerosis [69, 75]