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[PMID: 11955796] PubMed record related to this compound for laboratory literature review
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In a phase 2 trial of people with biopsy-confirmed MASH, tirzepatide treatment over 52 weeks led to resolution of MASH in 34 to 53% of participants (depending on the dose used) compared with placebo
According to Bloomberg, a spokesperson from the Michigan insurer cited consideration of the drugs effectiveness, safety and cost in reaching this decision, but did not respond to a question about what the safety concerns were. 2 According to the BCBS Michigan provider alert itself, the decision was based on a number of factors, including research indicating weight loss success is significantly higher when medication is used in combination with lifestyle changes such as diet and exercise rather than on its own
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