Its the active ingredient in Wegovy (approved specifically for weight loss) and Ozempic (approved for Type 2 diabetes, widely used off-label for weight management)
Visceral fat is strongly associated with increased cardiovascular disease risk, and its reduction typically correlates with improved cardiovascular health markers
Review findings The review confirms that incretin-based therapies have not only achieved their intended goal of T2D and obesity management but have also demonstrated clinically meaningful benefits across multiple organ systems
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Preclinical research in animals using GLP-1-estrogen conjugate molecules found that the combination decreased fasting blood glucose and improved insulin sensitivity to a greater extent than GLP-1 alone [4]