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Given its role in reducing blood sugar levels, it should come as no surprise that IGF1-LR3 reduces insulin levels as well as the need for exogenous insulin in diabetes

As the off-label use of these agents continues to grow in type 1 diabetes, particularly in patients with obesity or insulin resistance, our results support the need for continued investigation and consideration of their role as adjunctive therapies, Garg said

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IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid analogue engineered for an extended half-life relative to native IGF-1, making it a widely used reference compound in cellular-proliferation and growth-signalling research models

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