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(4) Furthermore, the oxidative stress imbalance, caused by excessive ROS production, impairs the antioxidant defense system by directly damaging antioxidant enzymes (such as SOD and GPx) and depleting key antioxidant molecules like glutathione, leading to fragmentation of hyaluronic acid in the extracellular matrix and abnormal collagen cross-linking, thereby reducing the mechanical properties of cartilage (6, 22, 23)
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(2024) 57(9):e13691
This exposure period was selected because it is consistent with the standardized ecotoxicological test protocol 201 guidelines of 2.3 Determination of Pb uptake Lead accumulation in the strains biomass was quantified following microwave-assisted acid digestion and subsequent determination by inductively coupled plasma mass spectrometry (ICP-MS), conducted in accordance with the guidelines of EPA Method 3,052 to ensure complete dissolution of biological and organic matrices ( 3 and 2 mL of HCl
Early findings suggest it could regulate immune balance during inflammatory and oxidative stress
