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To minimize any discomfort, practitioners often apply a topical numbing cream or use injectables that contain lidocaine, a mild anesthetic, to make the procedure more comfortable
2004, pp
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Another trial in 54 individuals confirmed its safety over 10 days of intravenous use at doses of up to 5.0g/kg (and up to 25.0g/kg in a single-dose trial)
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