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Skin Aging Claims Versus Systemic Anti-Aging Claims Skin aging claims can point to topical studies on photoaging and wrinkle parameters, but systemic anti-aging claims often rely on gene expression, oxidative stress, inflammation, or animal data [2], [10], 17

While these effects are not permanent, they can be regained with proper skin care, such as topical solutions and sunscreen

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Unlike topical treatments that may show results in weeks, systemic glutathione typically requires several months of regular use before significant improvements in hyperpigmentation become visible

Side Effects : Common side effects may include nausea, vomiting, fatigue, headache, dizziness, and chills