It is often referred to as the "master antioxidant" because of its extraordinary ability to neutralize free radicals, detoxify the liver, boost immune function, and regenerate other antioxidants like Vitamin C and E
Sources: Coskun T, et al
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That most anti-cancer drugs are poor substrates for GSTP indicates that the role of elevated GSTP in many tumor cell lines is not to detoxify the compounds, but must have another purpose
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Interestingly, the residues at multiple positions (12, 16, 17, 20, 21, 24 and 28) of the multi-targeting agonists are highly solvent-accessible and of limited contact with GLP-1R, allowing them to employ distinct amino acids from GLP-1 without altering GLP-1R signaling profiles