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These mixed responses cannot be generalized, but the fact that a subset experience real improvement makes this an important signal to investigate

Adults can synthesize sufficient L-carnitine to maintain normal metabolic levels, but infants have a weaker synthetic capacity, only about 12-15% of that of adults

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The presenters noted this was more common in the higher doses of retatrutide and more common in patients already on anti-hypertension medications and tended to resolve after stopping the blood pressure medication or increasing fluid intake

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