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4) and non-CKD patients (RR 0.91, 95% CI 0.771.08

This slows the rate at which the stomach empties and then signals to the brain to reduce appetite. While GLP-1s like Ozempic are FDA-approved to treat type 2 diabetes and manage high blood sugar levels, doctors often prescribe them for off-label useone of the most common being for weight loss

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Expression of DPP-4 is substantially dysregulated in a variety of disease states, including inflammation, cancer, obesity, and diabetes [22]

Physicians should establish baseline levels of IGF-1, fasting insulin, HbA1c, and a comprehensive metabolic panel prior to initiation