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With a vegetarian diet or low consumption of animal products

Additional: Recent coverage (e.g., NY Post Feb 2026 on discontinuation signals), company updates.

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Some researchers prefer morning dosing on an empty stomach for energy-pathway timing, but this is preference-driven rather than evidence-driven

It also stabilizes endothelial cell junctions, reducing fluid leakage and swelling

Because only one company manufactures the branded version, supply chain issues have frequently led to nationwide shortages