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Its defining modification is a trans -3-hexenoyl group attached to the N-terminal tyrosine, a chemical change designed to protect the peptide from rapid cleavage by dipeptidyl peptidase-4 (DPP-4), the enzyme that quickly inactivates native GHRH

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Once the shot is administered, some people report the area feeling slightly sore and tender, as well as a little bit of redness

IGF-1: Insulin-like growth factor 1, a downstream marker commonly measured in GH axis research