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Adults receiving orforglipron 12 mg had a 6.1% decline in body weight and those receiving orforglipron 36 mg had a body weight decrease of 8.2% from baseline to 1 year compared with a 3.9% weight loss with semaglutide 7 mg and a 5.3% reduction in weight with semaglutide 14 mg, according to the treatment-regimen estimand

Ueno Y, Koike M, Shimada Y, Shimura H, Hira K, Tanaka R, et al

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Eating more oily fish like salmon, sardines, and mackerel can be beneficial