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Many users report barely noticing a difference during their first week on semaglutide

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International heart journal

GLP-1-related shedding tends to be diffuse (all over the scalp) and starts a few months after a trigger like rapid weight loss

(PubMed) Kupka R, Mugusi F, Aboud S, Hertzmark E, Spiegelman D, Fawzi WW

These medications work by adjusting appetite, digestion, and blood sugar regulation, so when that support is removed, those systems can shift back quickly