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2022;11(1):e210073
Studies have shown that cancer itself can cause effector T (Teff) cell metabolism disorders, and there is a negative correlation between the degree of glycolytic activity of cancer cells and the antitumor function of infiltrating T cells (282)
An increase in the respiratory exchange ratio (RER), indicative of increased carbohydrate utilization, was detected in mAb-treated males (Supplementary Fig
Findings suggest that it may initiate signaling cascades involving PI3K and AMPK, pathways associated with nutrient regulation and energy use
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