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It also declines with age
Treatment response evaluation should focus on objective measures relevant to the specific indication being treated
518 These findings suggest that activation of the PERK-eIF2 pathway protects (re)myelinating oligodendrocytes from the harmful effects of IFN in immune-mediated demyelinating diseases
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(the New York Times) - behind the Headlines - NLM. NCBI, www.ncbi.nlm.nih.gov/search/research-news/8501/
Notably, the ALKIVIA study also demonstrated positive phase II/III results for VYVGART Hytrolu within idiopathic inflammatory myopathies, triggering its further development within this indication [253], for which efgartigimod is the FcRn antagonist with the most advanced clinical program as of January 2025
