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Baicalein reduces lipid peroxidation and prevents iron-dependent cell death (ferroptosis) in post-traumatic epilepsy by inhibiting 12/15-lipoxygenase (12/15-LOX) and decreasing lipid reactive oxygen species (Lipid ROS), 4-hydroxynonenal (4-HNE), and prostaglandin-endoperoxide synthase 2 (PTGS2) in HT22 cells ( In short, flavones exhibit a multifaceted therapeutic impact on epilepsy by engaging with various signaling pathways, such as Nrf2, HO-1, PKA/CREB/BDNF, PI3K/AKT, MAPK, and SIRT1, which are vital for neutralizing oxidative stress
Briefly, for Co-IP assays, 100 l of plasmid DNA (2 g l 1 ) was mixed with 1 ml of protoplasts (2 105 cells per ml) for PEG-mediated transfection
Blood Circulation: It plays a role in improving blood circulation throughout the body
(PubMed) Keys A
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