How should I adjust portion sizes when eating fast food on GLP-1 treatment
Pathobiol Aging Age Relat Dis
The rate is accelerating because you have transitioned to a higher dose (0.5 mg by now, possibly 1.0 mg depending on your protocol)

Research Applications Lipolysis Mechanism Investigation AOD9604 serves as a research tool for investigating 3-adrenergic-receptor-dependent lipolytic pathways: Hormone-Sensitive Lipase: Examination of HSL activation, phosphorylation status, and lipid droplet association ATGL Regulation: Research on adipose triglyceride lipase expression and activity modulation Perilipin Phosphorylation: Investigation of lipid droplet coating protein regulation 3-Adrenergic Receptor Dependence: Studies indicating AOD9604s lipolytic effect requires functional 3-adrenergic receptors (abolished in 3-AR knockout models) and is associated with increased 3-AR expression Signaling Cascades: Examination of kinase cascades, calcium signaling, and downstream effectors Research protocols investigate how AOD9604 stimulates lipolysis through mechanisms distinct from catecholamines, providing insights into alternative fat mobilization pathways

Hunger and food intake may increase after treatment stops, and some weight regain is common
Measurable changes in body composition typically follow in the first month and become more pronounced as dosing is optimized