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Safety and side effects Peptides can offer significant health benefits, but like any other biologically active therapy, they can cause some side effects

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Patients may develop compensatory movement patterns that strain joints and soft tissues

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This hypothesis is supported by several studies that have shown supplementation with SAM improves depressive symptoms (104-107)

The semaglutide versus tirzepatide side effect comparison shows that tirzepatide generally produces greater weight loss with a broadly similar side effect profile, though individual response varies