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Gastaldelli A, Gaggini M, Daniele G, Ciociaro D, Cersosimo E, Tripathy D, et al

G6PD deficiency shifts polarization of monocytes/macrophages towards a proinflammatory and profibrotic phenotype

Activa centros de saciedad en el cerebro, especialmente en el hipotlamo y el tronco enceflico, promoviendo as la reduccin del apetito y la ingesta calrica

Serratiopeptidase only works because the oral dose is high enough that the small fraction of the drug which survives the gut reaches systemic circulation at concentrations sufficient for therapeutic effect

EMPA-KIDNEY Collaborative Group (2023) Empagliflozin in patients with chronic kidney disease

Kidney function considerations are important, particularly in patients with pre-existing renal impairment