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There were several notable updates and trials involving GLP-1 RAs in the stroke field in 2025, none bigger than semaglutide's 14 Data from the phase 3 SOUL trial (NCT03914326) was the leading driver behind this decision

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Changes required by state or federal law, or pursuant to revisions of Current Procedural Terminology (CPT) codes published by the American Medical Association, may be effective outside the statutory dates outlined above.

Researchers also study TB-500 , a synthetic peptide based on the active region of the naturally occurring actin-binding protein thymosin beta-4

Kubinyi, H