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For Marcus, this program meant a real shiftnot just a number on the scale, but more energy and hope
Although some GLP-1RAs do not seem to naturally cross the bloodbrain barrier, they may still reach relevant brain areas via circumventricular sites and, possibly, via active transporters 4,5
Biochemistry 50 , 618627 (2011)
Cogen AL, Desai K, Elder D, et al
Regular monitoring : Track weight, measurements, and non-scale victories (improved energy, better sleep, reduced medication needs for comorbidities)
Furthermore, a recent extensive cohort study involving over 33,000 GLP-1 RA users diagnosed with diabetes over a 9-year period indicated no significant increase in pancreatic cancer risk associated with GLP-1 RA use, as evidenced by an HR of 0.50 compared to basal insulin [60]
