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The central clinical idea: toxic overload may affect mood when oxidative stress, inflammation, mitochondrial strain, glutathione depletion and impaired clearance reduce the brains biochemical resilience

Administration methods include intramuscular (IM) and intravenous (IV) injections

Alternatively, introducing a refeed day or temporary caloric increase can reset metabolic adaptation and restore progress

Reduced glutathione (also called GSH) is the active, electron-donating form of the molecule