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Comparing costs to alternatives provides perspective

Using smaller dose adjustments could reduce nausea, vomiting, and diarrhoea, which may be beneficial for people who experience severe gastrointestinal symptoms

Many users find the step-up process easier to tolerate, likely due to the balanced hormonal effects

This caloric deficit, rather than an increase in metabolic rate, is the main driver of weight loss observed in clinical trials

MASH resolved in patients treated with tirzepatide at one of three doses Launched in 2019, the SYNERGY-NASH trial evaluated tirzepatide in 196 overweight adults, ages 18-80, with biopsy-proven MASH and stage 2 or 3 liver fibrosis, reflecting moderate to significant fibrosis that hasnt progressed to cirrhosis