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In addition, this is the first study demonstrating that downregulation of GR may be involved in heart aging as cardiac-specific expression of GR effectively protected the heart against aging-associated cardiomyopathy (Online Figures VI through IX)

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The kinetic data were analyzed by using the GraphPad Prism software with a simple pseudo first-order reaction model to estimate the apparent kinetic parameters

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However, the temperature ranges considered in this experiment may not have induced oxidative stress conditions (e.g., Jin et al