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Specifically, GLP-1 receptors are enriched in the lateral septum (where expression is highest), hypothalamus, amygdala, bed nucleus of the stria terminalis, hippocampus, ventral tegmental area (VTA), and nucleus accumbens (NAc)
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GLP-1 receptor agonist medications, including semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro), can be injected into the upper arm as an approved subcutaneous injection site