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While our study was observational and does not definitively confirm an association between GLP-1 medications and reduced breast cancer incidence, it does add to the growing body of evidence suggesting that its worth investigating these weight-loss drugs as potential cancer prevention tools, said Elizabeth McDonald, MD, PhD, professor of radiology at Penn Medicine and lead investigator of the study
In one phase 2 study: Pancreatitis was reported in about 0.4% of participants (1 out of 267) Gallbladder issues affected roughly 1.1%, with no cases in the placebo group Heart rhythm changes were reported more often in people taking retatrutide (about 6% compared to 3% with placebo) Liver enzyme increases were rare (around 1%), and overall liver health markers stayed stable over time
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PYY(3-36) potentiates Semaglutidemediated mitochondrial modulation in MASLD
This comprehensive strategy provides clarity, confidence, and care in a GLP-1-influenced food environment
