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Previously, we have reported that deletion of Dpp4 from the Tie2 + ECs ( Dpp4 EC/ ) of high-fatfed mice results in increased systemic concentrations of GLP-1 and improved glucose excursion but does not affect HGP (38)
Similarly, there have been several studies suggesting that exposure to tobacco products, which are triggers for asthma [202], increase components of BLP signaling in the lungs [203, 204]
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