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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result
Then I back down to 500mcg maybe once a week when I get as dark as I want just to maintain
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Consistent with these findings, another study demonstrated that increased oxygen and ATP consumption increased ROS, and induced mitochondria hyperpolarization in C9orf72 ALS patient-derived fibroblasts (Onesto et al., 2016)
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