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These drugs have also caused new or worsening kidney disease, including kidney failure, in some people

The latest evidence, however, suggests that as clinical use of GLP-1 drugs expands for both obesity and diabetes, it is imperative that treatment guidelines address not only initiation and titration but also discontinuation and long-term maintenance strategies to sustain therapeutic gains. Clinicians say the findings carry particularly significant implications for younger patients, who may wish or need to stop these medications after achieving desired weight-loss outcomes

This is because B12 is essential for the production of red blood cells (RBCs)

doi: 10.1016/j.freeradbiomed.2022.12.088 64 DuLGuoCZengSYuKLiuMLiY