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The dose of PYY-based compounds was escalated at day 4 from 100 nmol kg 1 to 500 nmol kg 1
TMAO levels were reduced in individuals who improved with treatment, underscoring the importance of monitoring PH severity and prognosis [17]
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The physiologic significance of these numerous actions has not been established.25 The pattern of PYY secretion in response to a meal raises the hypothesis that it may play a role as physiologic satiety signal, acting in terminating the meal and stimulating coordinated gastrointestinal responses in order to aid digestion and absorption
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