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In some cases, insurance may cover removal of the extra skin across the abdomen, which can improve quality of life and body shape

Suitability considerations: Consistent with class precedents for GLP-1-based therapies, retatrutide would not be expected to be suitable during pregnancy or breastfeeding, and paediatric data are currently lacking

Semaglutide is a prescription drug available as a once-weekly injection (Ozempic, Wegovy) or a once-daily tablet (Ozempic, Rybelsus)

Evidence Summary Current evidence supports the following conclusions: GLP-1 drugs reduce caloric intake Reduced intake may reduce micronutrient consumption Delayed gastric emptying does not equal malabsorption Rapid weight loss may increase lean mass vulnerability Long-term micronutrient outcome data remain limited There is mechanistic plausibility for nutritional risk in certain populations, but no strong evidence of universal depletion across all patients

What should I do if laxatives and hydration aren't working