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FOXO1 is downregulated in obese mice subjected to short-term strength training
A randomized controlled trial found that oral supplementation with 1,200 mg/day of lipoic acid for 10 weeks was of no benefit in treating HIV-associated cognitive impairment (103)
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For MACE-4, the HR was 0.80 (95% CI, 0.571.11) for tirzepatide versus standard therapy, the HR for cardiovascular death 0.90 (95% CI, 0.501.61) and 0.80 (95% CI, 0.511.25) for all-cause death
Neurology 1984
The Not-So-Good : They arent always the most effective for treating established GLP-1 constipation but can be helpful in preventing it or for mild cases of difficulty passing stool on GLP-1
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